Club EvMed: Die young, live fast: is accelerated reproduction an adaptive response to early life adversity in wild baboons? - Shared screen with speaker view
Charles Nunn
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Ronald Willis
Any particular events that lead to beneficial health effects in the long term?
Paul Watson
Are there differential patterns in cause of death depending on the type and extent of early life diversity?
Charles Nunn
Please feel free to post questions, comments and perspectives in the chat anytime! We will open for discussion when Chelsea and Beth finish their presentation.
Sahana Kuthyar
With investment in higher reproductive success, do you see trade-offs in other measures of fitness (e.g., growth/immune function)?
Bernie Crespi
What about stabilizing selection on pace of reproduction/
Allan Kugel
huh. Does accellerated reproduction increase risk if there's a subsequent tramatic event (like major food shortage)?
Meredith Spence Beaulieu, PhD (she/her/hers)
If you’d like to ask a question verbally, raise your hand virtually by clicking “Reactions” at the bottom panel, then “Raise Hand.”
Thomas Struhsaker
The regression between life span and adversity was only 0.15. So, what are the other variables contributing to the remaining 0.85 of the variance?
Randolph Nesse
Do you have thoughts about what might account for the findings in humans? Perhaps confounding factors or differences in environment?
Joseph Graves Jr
But in humans social and environment adversity are tightly correlated.
Stephanie Levy
Awesome talk! Have any other studies in non-human primates found similar results regarding the lack of a relationship between early life adversity and timing of reproductive maturity? Also, I apologize if you already mentioned this, but what are some examples of adverse early life events for baboons?
Joseph Graves Jr
Another aspect of the environmental diversity component is differential exposure to toxic materials, such as lead, organochloride compounds, etc.
Dawn Stancil
I wonder if the offspring of accelerated reproductive females also are accelerated themselves. Also is there evidence of social issues that may be a factor?
Ronald Willis
There are epigenetic effects in humans, can this be measured in wild baboons?
Joseph Graves Jr
But social navigation is not IQ, rather EQ.
Daniela Sieff
@Joseph Graves - exactly!
Nichole Evans
Joseph Graves Jr
Also measures of IQ are generally negatively associated with reproductive success.
Nichole Evans
Tauras Vilgalys
@Ronald Willis, Jordan Anderson in Jenny's lab (and others) are working on the gene regulatory consequences of early life on DNA methylation & gene expression now, stay tuned!
Joseph Graves Jr
Again that’s EQ
Calen Ryan
^@Ronald Willis: Variation in epigenetic processes can arise from genetic variation that also contribute to timing of reproduction. Or can arise along with environmental factors that contribute to both. The trap to avoid is using ‘epigenetic’ as another black box that doesn’t actually bring us closer to a mechanism.
Richard Katz
this seems essenntially jnvefrifiable
Joseph Graves Jr
Certainly lack of choice for females is strongly socially determined in patriarchal societies, and virtually every society is patriarchal.
Daniela Sieff
@Joseph Graves - would you say that early adversity in humans can lead to being disadvantaged in schools (nothing to do with IQ, EQ or ability to assess mate quality). But would mean less inclined to stay in education and delay reproduction, just because disadvantages mean you are likely to be less successful at school
Joseph Graves Jr
Certainly leaving school early could mean that you are more likely to have children at a younger age, but again I would argue because of the way social injustice operates in human societies no way to correlate this with either EQ or Iq.
Liz Lange
@Bernie Crespi come to the postdoc talks next week to hear more about how social relationships might mediate and mitigate early adversity effect's on survival
Tauras Vilgalys
@Calen, I'm going to disagree a bit and say that gene regulatory mechanisms can be useful to understand the lasting consequences of early life adversity. For example, social status affects immune function in response to infection and Amanda Lea's work has shown lasting metabolic consequences of early life diet. That's added insight and not just a black box(I'm avoiding the term epigenetic because that involves non-sequence, heritable changes to some audiences. What I think we're talking about here is gene regulatory differences, and relatively agnostic to the genetic contribution through GxE)
Paula Ivey Henry
Education itself is a structured source of adversity - maternal/familial social and health inequities, poor infant/child outcomes, higher risk neighborhoods, and poor education opportunities and investments are highly correlated. Perhaps test in H&Gs?
Ronald Willis
Any role for r/K selection in this? Modern humans seem to prefer having fewer children and later.
Sonia Cavigelli
Great talk! Thanks.
Joseph Graves Jr
Please see my paper debunking the notion of r-/K- selection, in general, and definitely not happening in humans. Graves 2002. Anthropological Theory.
Leslie Digby
Interesting research Beth and Chelsea - looking forward to hearing more in the future!
Moira Donovan
Thank you for the great talk!